RUNX3 抗体 (AA 186-252)
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- 抗原 See all RUNX3 抗体
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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抗原表位
- AA 186-252
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RUNX3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. coli.
- 克隆位点
- 2B3
- 亚型
- IgG2b
- Top Product
- Discover our top product RUNX3 Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 12, pp. 1823-30, (2011) (PubMed).
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RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 12, pp. 1823-30, (2011) (PubMed).
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- 抗原
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
- 别名
- RUNX3 (RUNX3 产品)
- 别名
- runxb antibody, RUNX3 antibody, CBFA3 antibody, frrunx3 antibody, runx3 antibody, aml2 antibody, cbfa3 antibody, pebp2ac antibody, AML2 antibody, Cbfa3 antibody, Pebp2a3 antibody, PEBP2aC antibody, runt-related transcription factor 3 antibody, runt related transcription factor 3 antibody, runt related transcription factor 3 L homeolog antibody, runx3 antibody, RUNX3 antibody, runx3.L antibody, Runx3 antibody
- 背景
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Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases: AML2, CBFA3, PEBP2aC, FLJ34510, MGC16070
- 分子量
- 44.4 kDa
- 基因ID
- 864
- HGNC
- 864
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