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- 抗原 See all CDC25C 抗体
- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CDC25C antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human CDC25C expressed in E. coli.
- 克隆位点
- 1F12
- 亚型
- IgG1
- Top Product
- Discover our top product CDC25C Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 9, pp. 2199-210, (2010) (PubMed).
: "The G2/M checkpoint phosphatase cdc25C is located within centrosomes." in: The international journal of biochemistry & cell biology, Vol. 39, Issue 9, pp. 1707-13, (2007) (PubMed).
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Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 9, pp. 2199-210, (2010) (PubMed).
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- 抗原
- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
- 别名
- CDC25C (CDC25C 产品)
- 别名
- CDC25C antibody, cdc25 antibody, xcdc25c antibody, CDC25 antibody, PPP1R60 antibody, Cdc25 antibody, cdc25-3 antibody, xcdc25-3 antibody, cell division cycle 25C antibody, cell division cycle 25C S homeolog antibody, CDC25C antibody, cdc25c antibody, Cdc25c antibody, cdc25c.S antibody
- 背景
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Description: Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Aliases: CDC25, CDC25C
- 分子量
- 58 kDa
- 基因ID
- 995
- HGNC
- 995
- 途径
- Cell Division Cycle, M Phase
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