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CD247 抗体

CD247 适用: 人 ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 4B10 unconjugated
产品编号 ABIN1724734
发货至: 中国
  • 抗原 See all CD247 抗体
    CD247 (CD247 Molecule (CD247))
    适用
    • 88
    • 39
    • 16
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 72
    • 13
    • 5
    • 1
    小鼠
    克隆类型
    • 71
    • 20
    单克隆
    标记
    • 50
    • 8
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CD247 antibody is un-conjugated
    应用范围
    • 69
    • 49
    • 29
    • 13
    • 9
    • 9
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    CD247 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CD247 expressed in E. Coli.
    克隆位点
    4B10
    亚型
    IgG1
    Top Product
    Discover our top product CD247 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, (2005) (PubMed).

    Nambiar, Fisher, Warke, Krishnan, Mitchell, Delaney, Tsokos: "Reconstitution of deficient T cell receptor zeta chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus." in: Arthritis and rheumatism, Vol. 48, Issue 7, pp. 1948-55, (2003) (PubMed).

    Dumont, Blanchard, Di Bartolo, Lezot, Dufour, Jauliac, Hivroz: "TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 4, pp. 1705-12, (2002) (PubMed).

  • 抗原
    CD247 (CD247 Molecule (CD247))
    别名
    CD247 (CD247 产品)
    别名
    CD3-ZETA antibody, CD3H antibody, CD3Q antibody, CD3Z antibody, T3Z antibody, TCRZ antibody, 4930549J05Rik antibody, A430104F18Rik antibody, AW552088 antibody, Cd3 antibody, Cd3-eta antibody, Cd3-zeta antibody, Cd3h antibody, Cd3z antibody, Cd3zeta antibody, T3z antibody, Tcrk antibody, Tcrz antibody, LOC100136514 antibody, LOC100136549 antibody, LOC100305023 antibody, CD247 antibody, TCRzeta antibody, CD247 molecule antibody, CD247 antigen antibody, CD3zeta-2 antibody, CD3zeta-1 antibody, Cd247 molecule antibody, CD247 antibody, Cd247 antibody, cd3z antibody, cd247 antibody
    背景

    Description: The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Aliases: T3Z, CD3H, CD3Q, CD3Z, TCRZ, CD3-ZETA, CD247

    分子量
    18kDa
    基因ID
    919
    HGNC
    919
    UniProt
    P20963
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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