CD247 抗体
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- 抗原 See all CD247 抗体
- CD247 (CD247 Molecule (CD247))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD247 antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 原理
- CD247 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human CD247 expressed in E. Coli.
- 克隆位点
- 4B10
- 亚型
- IgG1
- Top Product
- Discover our top product CD247 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, (2005) (PubMed).
: "Reconstitution of deficient T cell receptor zeta chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus." in: Arthritis and rheumatism, Vol. 48, Issue 7, pp. 1948-55, (2003) (PubMed).
: "TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 4, pp. 1705-12, (2002) (PubMed).
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Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, (2005) (PubMed).
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- 抗原
- CD247 (CD247 Molecule (CD247))
- 别名
- CD247 (CD247 产品)
- 背景
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Description: The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Aliases: T3Z, CD3H, CD3Q, CD3Z, TCRZ, CD3-ZETA, CD247
- 分子量
- 18kDa
- 基因ID
- 919
- HGNC
- 919
- UniProt
- P20963
- 途径
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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