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PARP1 抗体

PARP1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7A10 unconjugated
产品编号 ABIN1724733
发货至: 中国
  • 抗原 See all PARP1 抗体
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    适用
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    宿主
    • 202
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    小鼠
    克隆类型
    • 196
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    单克隆
    标记
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    This PARP1 antibody is un-conjugated
    应用范围
    • 150
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    PARP Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Synthetic peptide of human PARP, conjugated to KLH.
    克隆位点
    7A10
    亚型
    IgG1
    Top Product
    Discover our top product PARP1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Hassa, Covic, Hasan, Imhof, Hottiger: "The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 45588-97, (2001) (PubMed).

  • 抗原
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    别名
    PARP (PARP1 产品)
    别名
    ADPRT antibody, ADPRT 1 antibody, ADPRT1 antibody, ARTD1 antibody, PARP antibody, PARP-1 antibody, PPOL antibody, pADPRT-1 antibody, Adprt antibody, Parp-1 antibody, 5830444G22Rik antibody, AI893648 antibody, Adprp antibody, Adprt1 antibody, C80510 antibody, parp-1 antibody, sPARP-1 antibody, BEST:LD21673 antibody, CG17685 antibody, CG17696 antibody, CG17718 antibody, CG40411 antibody, D.PARP antibody, Dm.pARTa antibody, Dmel\\CG40411 antibody, LD21673.3prime antibody, PARP1 antibody, dPARP antibody, parp antibody, adprt1 antibody, padprt-1 antibody, ppol antibody, si:dkey-206f10.3 antibody, wu:fc60f12 antibody, zgc:110092 antibody, poly(ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase 1 antibody, poly (ADP-ribose) polymerase family, member 1 antibody, Poly-(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 1 L homeolog antibody, PARP1 antibody, Parp1 antibody, Parp antibody, parp1.L antibody, parp1 antibody
    背景

    Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

    Aliases: PARP, PPOL, ADPRT, ADPRT1, PARP-1, pADPRT-1, PARP1

    分子量
    117kDa
    基因ID
    142
    HGNC
    142
    UniProt
    P09874
    途径
    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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