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AKT2 抗体

AKT2 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1B6 unconjugated
产品编号 ABIN1724720
发货至: 中国
  • 抗原 See all AKT2 抗体
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    适用
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    宿主
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    小鼠
    克隆类型
    • 163
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    单克隆
    标记
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    This AKT2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    AKT2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human AKT2 expressed in E. Coli.
    克隆位点
    1B6
    亚型
    IgG2b
    Top Product
    Discover our top product AKT2 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Gosmanov, Umpierrez, Karabell, Cuervo, Thomason: "Impaired expression and insulin-stimulated phosphorylation of Akt-2 in muscle of obese patients with atypical diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 287, Issue 1, pp. E8-E15, (2004) (PubMed).

    Xu, Sakon, Nagano, Hiraoka, Yamamoto, Hayashi, Dono, Nakamori, Umeshita, Ito, Matsuura, Monden: "Akt2 expression correlates with prognosis of human hepatocellular carcinoma." in: Oncology reports, Vol. 11, Issue 1, pp. 25-32, (2003) (PubMed).

  • 抗原
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    别名
    AKT2 (AKT2 产品)
    别名
    AKT2 antibody, pkbb antibody, pkbbeta antibody, pkbss antibody, prkbb antibody, rac-beta antibody, v-akt2 antibody, 2410016A19Rik antibody, AW554154 antibody, PKB antibody, PKBbeta antibody, HIHGHH antibody, PKBB antibody, PKBBETA antibody, PRKBB antibody, RAC-BETA antibody, cb945 antibody, akt2-a antibody, AKT serine/threonine kinase 2 antibody, v-akt murine thymoma viral oncogene homolog 2 antibody, thymoma viral proto-oncogene 2 antibody, v-akt murine thymoma viral oncogene homolog 2 L homeolog antibody, AKT2 antibody, akt2 antibody, Akt2 antibody, akt2.L antibody
    背景

    Description: Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53 kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.

    Aliases: PKBB, PRKBB, PKBBETA, RAC-BETA

    分子量
    60kDa
    基因ID
    208
    HGNC
    208
    UniProt
    P31751
    途径
    PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling
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