HSC70 Interacting Protein HIP 抗体
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- 抗原 See all HSC70 Interacting Protein HIP (ST13) 抗体
- HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HSC70 Interacting Protein HIP antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 原理
- ST13 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human ST13 expressed in E. Coli.
- 克隆位点
- 3B10
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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An investigation into the human serum "interactome"." in: Electrophoresis, Vol. 25, Issue 9, pp. 1289-98, (2004) (PubMed).
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An investigation into the human serum "interactome"." in: Electrophoresis, Vol. 25, Issue 9, pp. 1289-98, (2004) (PubMed).
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- 抗原
- HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
- 别名
- ST13 (ST13 产品)
- 背景
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Description: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several co-chaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.
Aliases: HIP, HOP, P48, AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST13
- 分子量
- 48kDa
- 基因ID
- 6767
- HGNC
- 6767
- UniProt
- P50502
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