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HSC70 Interacting Protein HIP 抗体

ST13 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B10 unconjugated
产品编号 ABIN1724716
发货至: 中国
  • 抗原 See all HSC70 Interacting Protein HIP (ST13) 抗体
    HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
    适用
    • 43
    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 35
    • 9
    小鼠
    克隆类型
    • 36
    • 8
    单克隆
    标记
    • 25
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSC70 Interacting Protein HIP antibody is un-conjugated
    应用范围
    • 43
    • 16
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    ST13 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human ST13 expressed in E. Coli.
    克隆位点
    3B10
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Zhou, Lucas, Chan, Issaq, Petricoin, Liotta, Veenstra, Conrads: "An investigation into the human serum "interactome"." in: Electrophoresis, Vol. 25, Issue 9, pp. 1289-98, (2004) (PubMed).

  • 抗原
    HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
    别名
    ST13 (ST13 产品)
    背景

    Description: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several co-chaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.

    Aliases: HIP, HOP, P48, AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST13

    分子量
    48kDa
    基因ID
    6767
    HGNC
    6767
    UniProt
    P50502
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