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F2RL3 抗体 (AA 1-330)

F2RL3 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3G9H7 unconjugated
产品编号 ABIN1724706
发货至: 中国
  • 抗原 See all F2RL3 抗体
    F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
    抗原表位
    • 15
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-330
    适用
    • 49
    • 33
    • 33
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 46
    • 3
    小鼠
    克隆类型
    • 46
    • 3
    单克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This F2RL3 antibody is un-conjugated
    应用范围
    • 41
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of PAR4(aa1-330) expressed in E. coli.
    克隆位点
    3G9H7
    亚型
    IgG1
    Top Product
    Discover our top product F2RL3 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Weller, Dahl, Lohoff, Kampman, Oslin, Dackis, Ferraro, OBrien, Berrettini: "No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence." in: Psychiatric genetics, Vol. 16, Issue 5, pp. 193-6, (2006) (PubMed).

    Gurumurthy, Goswami, Vasudevan, Rangnekar: "Phosphorylation of Par-4 by protein kinase A is critical for apoptosis." in: Molecular and cellular biology, Vol. 25, Issue 3, pp. 1146-61, (2005) (PubMed).

    Xie, Guo: "Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28266-75, (2004) (PubMed).

    Kukoc-Zivojnov, Puccetti, Chow, Bergmann, Ruthardt, Hoelzer, Mitrou, Weidmann, Boehrer: "Prostate apoptosis response gene-4 (par-4) abrogates the survival function of p185(BCR-ABL) in hematopoietic cells." in: Experimental hematology, Vol. 32, Issue 7, pp. 649-56, (2004) (PubMed).

  • 抗原
    F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
    别名
    PAR4 (F2RL3 产品)
    别名
    F2RL3 antibody, PAR4 antibody, F2R like thrombin or trypsin receptor 3 antibody, F2R like thrombin/trypsin receptor 3 antibody, coagulation factor II (thrombin) receptor-like 3 antibody, F2RL3 antibody, F2rl3 antibody
    背景

    Description: Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.

    Aliases: PAWR

    基因ID
    5074
    HGNC
    5074
    途径
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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