F2RL3 抗体 (AA 1-330)
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- 抗原 See all F2RL3 抗体
- F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
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抗原表位
- AA 1-330
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This F2RL3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 原理
- PAR4 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of PAR4(aa1-330) expressed in E. Coli.
- 克隆位点
- 3G9H7
- 亚型
- IgG1
- Top Product
- Discover our top product F2RL3 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence." in: Psychiatric genetics, Vol. 16, Issue 5, pp. 193-6, (2006) (PubMed).
: "Phosphorylation of Par-4 by protein kinase A is critical for apoptosis." in: Molecular and cellular biology, Vol. 25, Issue 3, pp. 1146-61, (2005) (PubMed).
: "Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28266-75, (2004) (PubMed).
: "Prostate apoptosis response gene-4 (par-4) abrogates the survival function of p185(BCR-ABL) in hematopoietic cells." in: Experimental hematology, Vol. 32, Issue 7, pp. 649-56, (2004) (PubMed).
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No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence." in: Psychiatric genetics, Vol. 16, Issue 5, pp. 193-6, (2006) (PubMed).
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- 抗原
- F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
- 别名
- PAR4 (F2RL3 产品)
- 别名
- F2RL3 antibody, PAR4 antibody, F2R like thrombin or trypsin receptor 3 antibody, F2R like thrombin/trypsin receptor 3 antibody, coagulation factor II (thrombin) receptor-like 3 antibody, F2RL3 antibody, F2rl3 antibody
- 背景
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Description: Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.
Aliases: PAWR
- 基因ID
- 5074
- HGNC
- 5074
- UniProt
- Q96IZ0
- 途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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