MAPK10 抗体 (AA 28-233)
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- 抗原 See all MAPK10 抗体
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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抗原表位
- AA 28-233
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MAPK10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 原理
- MAPK10 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli.
- 克隆位点
- 10E4A4
- 亚型
- IgG1
- Top Product
- Discover our top product MAPK10 Primary Antibody
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).
: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).
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The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).
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- 抗原
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
- 别名
- MAPK10 (MAPK10 产品)
- 别名
- MAPK10 antibody, zgc:123234 antibody, DKFZp459H0638 antibody, Jnk3 antibody, SAPKC antibody, SAPb antibody, Serk2 antibody, JNK3 antibody, JNK3A antibody, PRKM10 antibody, SAPK1b antibody, p493F12 antibody, p54bSAPK antibody, C230008H04Rik antibody, JNK3B1 antibody, JNK3B2 antibody, SAPK(beta) antibody, ATMPK10 antibody, MAP kinase 10 antibody, mitogen-activated protein kinase 8 S homeolog antibody, mitogen-activated protein kinase 10 antibody, mitogen activated protein kinase 10 antibody, MAP kinase 10 antibody, mapk8.S antibody, MAPK10 antibody, mapk10 antibody, Mapk10 antibody, MPK10 antibody
- 背景
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Description: MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Aliases: JNK3, JNK3A, PRKM10, p54bSAPK
- 分子量
- 53kDa
- 基因ID
- 5602
- NCBI登录号
- NP_002744
- HGNC
- 5602
- UniProt
- P53779
- 途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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