MAPK10 抗体 (AA 28-233)
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- 抗原 See all MAPK10 抗体
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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抗原表位
- AA 28-233
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MAPK10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 原理
- MAPK10 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli.
- 克隆位点
- 10E4A4
- 亚型
- IgG1
- Top Product
- Discover our top product MAPK10 Primary Antibody
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).
: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).
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The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).
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- 抗原
- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
- 别名
- MAPK10 (MAPK10 产品)
- 背景
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Description: MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Aliases: JNK3, JNK3A, PRKM10, p54bSAPK
- 分子量
- 53kDa
- 基因ID
- 5602
- NCBI登录号
- NP_002744
- HGNC
- 5602
- UniProt
- P53779
- 途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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