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MAPK10 抗体 (AA 28-233)

MAPK10 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 10E4A4 unconjugated
产品编号 ABIN1724701
发货至: 中国
  • 抗原 See all MAPK10 抗体
    MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
    抗原表位
    • 15
    • 11
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-233
    适用
    • 62
    • 50
    • 34
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 66
    • 7
    • 3
    小鼠
    克隆类型
    • 61
    • 17
    单克隆
    标记
    • 33
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAPK10 antibody is un-conjugated
    应用范围
    • 46
    • 37
    • 25
    • 13
    • 13
    • 8
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    原理
    MAPK10 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human MAPK10 (aa28-233) expressed in E. Coli.
    克隆位点
    10E4A4
    亚型
    IgG1
    Top Product
    Discover our top product MAPK10 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tamma, Kalyanaraman, Pahwa, Dominguez, Modesto: "The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).

    Kinet, Bernard, Mongellaz, Perreau, Goldman, Taylor: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).

  • 抗原
    MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
    别名
    MAPK10 (MAPK10 产品)
    别名
    MAPK10 antibody, zgc:123234 antibody, DKFZp459H0638 antibody, Jnk3 antibody, SAPKC antibody, SAPb antibody, Serk2 antibody, JNK3 antibody, JNK3A antibody, PRKM10 antibody, SAPK1b antibody, p493F12 antibody, p54bSAPK antibody, C230008H04Rik antibody, JNK3B1 antibody, JNK3B2 antibody, SAPK(beta) antibody, ATMPK10 antibody, MAP kinase 10 antibody, mitogen-activated protein kinase 8 S homeolog antibody, mitogen-activated protein kinase 10 antibody, mitogen activated protein kinase 10 antibody, MAP kinase 10 antibody, mapk8.S antibody, MAPK10 antibody, mapk10 antibody, Mapk10 antibody, MPK10 antibody
    背景

    Description: MAPK10: mitogen-activated protein kinase 10, also known as JNK3, JNK3A, PRKM10, p54bSAPK. Entrez Protein NP_002744. It is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Aliases: JNK3, JNK3A, PRKM10, p54bSAPK

    分子量
    53kDa
    基因ID
    5602
    NCBI登录号
    NP_002744
    HGNC
    5602
    UniProt
    P53779
    途径
    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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