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- 抗原 See all Survivin (BIRC5) 抗体
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Survivin antibody is un-conjugated
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应用范围
- ELISA
- 原理
- Survivin Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of Survivin expressed in E. Coli.
- 克隆位点
- 2H5H2
- 亚型
- IgG1
- Top Product
- Discover our top product BIRC5 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder." in: Urology, Vol. 70, Issue 3, pp. 482-6, (2007) (PubMed).
: "Nuclear survivin is associated with disease recurrence and poor survival in patients with cutaneous malignant melanoma." in: Histopathology, Vol. 50, Issue 7, pp. 835-42, (2007) (PubMed).
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Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder." in: Urology, Vol. 70, Issue 3, pp. 482-6, (2007) (PubMed).
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- 抗原
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
- 别名
- Survivin (BIRC5 产品)
- 背景
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Description: Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Aliases: API4, EPR-1, BIRC5
- 基因ID
- 332
- HGNC
- 332
- UniProt
- O15392
- 途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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