-
- 抗原 See all TNF alpha 抗体
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TNF alpha antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 免疫原
- Recombinant Human TNF-alpha
- 克隆位点
- 2A9B9
- 亚型
- IgG1
- Top Product
- Discover our top product TNF alpha Primary Antibody
-
-
- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
-
-
Amitriptyline administration transforms tumor necrosis factor-alpha regulation of norepinephrine release in the brain." in: Brain research, Vol. 1023, Issue 1, pp. 112-20, (2004) (PubMed).
: "Nitric oxide-dependent synthesis of vascular endothelial growth factor is impaired by high glucose." in: Life sciences, Vol. 75, Issue 21, pp. 2573-86, (2004) (PubMed).
: "Interleukin-10: biomarker or pathologic cytokine in fulminant myocarditis?" in: Journal of the American College of Cardiology, Vol. 44, Issue 6, pp. 1298-300, (2004) (PubMed).
: "
-
Amitriptyline administration transforms tumor necrosis factor-alpha regulation of norepinephrine release in the brain." in: Brain research, Vol. 1023, Issue 1, pp. 112-20, (2004) (PubMed).
-
- 抗原
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
- 别名
- TNF-alpha (TNF alpha 产品)
- 别名
- DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
- 背景
-
Description: TNF-alpha (tumor necrosis factor alpha) is an important cytokine produced by numerous cell types including neutrophils, activated lymphocytes, macrophages and NK cells. It plays a critical role in inflammatory responses and in apoptosis. TNF-alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF-alpha exists as a multimer of two, three, or five non covalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. Although it has little effect on many cultured normal human cells, TNF-alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF-alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF-alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
Aliases: DIF, TNFA, TNFSF2, TNF-alpha
- 基因ID
- 7124
- HGNC
- 7124
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
-