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- 抗原 See all KAT5 抗体
- KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KAT5 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 原理
- TIP60 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human TIP60 expressed in E. Coli.
- 克隆位点
- 3F9
- 亚型
- IgG2b
- Top Product
- Discover our top product KAT5 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Patterning chromatin: form and function for H2A.Z variant nucleosomes." in: Current opinion in genetics & development, Vol. 16, Issue 2, pp. 119-24, (2006) (PubMed).
: "In and out: histone variant exchange in chromatin." in: Trends in biochemical sciences, Vol. 30, Issue 12, pp. 680-7, (2005) (PubMed).
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Patterning chromatin: form and function for H2A.Z variant nucleosomes." in: Current opinion in genetics & development, Vol. 16, Issue 2, pp. 119-24, (2006) (PubMed).
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- 抗原
- KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
- 别名
- TIP60 (KAT5 产品)
- 别名
- 6121 antibody, CG6121 antibody, DmEG0007.7 antibody, Dmel/TIP60 antibody, Dmel\\CG6121 antibody, Dmel\\TIP60 antibody, EG0007.7 antibody, EG:EG0007.7 antibody, TIP60 antibody, dTIP60 antibody, dTip60 antibody, dmHAG405 antibody, im:6908768 antibody, wu:fb55b08 antibody, zgc:110752 antibody, ESA1 antibody, HTATIP antibody, HTATIP1 antibody, PLIP antibody, TIP antibody, ZC2HC5 antibody, cPLA2 antibody, AI839539 antibody, CPLA2 antibody, Htatip antibody, Htatip1 antibody, Tip55 antibody, Tip60 antibody, K(lysine) acetyltransferase 5a antibody, lysine acetyltransferase 5 antibody, Tat interactive protein 60kDa antibody, histone acetyltransferase Tip60 antibody, tip60, putative antibody, K(lysine) acetyltransferase 5b antibody, K(lysine) acetyltransferase 5 antibody, kat5a antibody, KAT5 antibody, Tip60 antibody, LOC413101 antibody, LOC5579231 antibody, Smp_053140 antibody, kat5b antibody, Kat5 antibody
- 背景
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Description: HTATIP (HIV-1 Tat interacting protein TIP60, about 60 kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A: canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
Aliases: TIP60 (HTATIP)
- 分子量
- 60kDa
- 基因ID
- 10524
- HGNC
- 10524
- UniProt
- Q92993
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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