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MYST1 抗体

KAT8 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 8C4C4 unconjugated
产品编号 ABIN1724671
发货至: 中国
  • 抗原 See all MYST1 (KAT8) 抗体
    MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))
    适用
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    宿主
    • 62
    • 5
    小鼠
    克隆类型
    • 55
    • 12
    单克隆
    标记
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    This MYST1 antibody is un-conjugated
    应用范围
    • 53
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    原理
    MYST1 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human MYST1 expressed in E. Coli.
    克隆位点
    8C4C4
    亚型
    IgG2b
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Jiang, Gao, Zheng, Yin, Wang, Zhong, Ali, Khan, Hao, Fang, Sun, Xu, Pandita, Jiang, Shi: "MOF influences meiotic expansion of H2AX phosphorylation and spermatogenesis in mice." in: PLoS genetics, Vol. 14, Issue 5, pp. e1007300, (2018) (PubMed).

    Akhtar, Becker: "The histone H4 acetyltransferase MOF uses a C2HC zinc finger for substrate recognition." in: EMBO reports, Vol. 2, Issue 2, pp. 113-8, (2001) (PubMed).

    Neal, Pannuti, Smith, Lucchesi: "A new human member of the MYST family of histone acetyl transferases with high sequence similarity to Drosophila MOF." in: Biochimica et biophysica acta, Vol. 1490, Issue 1-2, pp. 170-4, (2000) (PubMed).

    Sterner, Berger: "Acetylation of histones and transcription-related factors." in: Microbiology and molecular biology reviews : MMBR, Vol. 64, Issue 2, pp. 435-59, (2000) (PubMed).

  • 抗原
    MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))
    别名
    MYST1 (KAT8 产品)
    别名
    myst1 antibody, wu:fb22g02 antibody, wu:fj22d09 antibody, zgc:66387 antibody, Myst1 antibody, MOF antibody, MYST1 antibody, ZC2HC8 antibody, hMOF antibody, 2010203C02Rik antibody, 5830450F21Rik antibody, D7Ertd629e antibody, K(lysine) acetyltransferase 8 antibody, lysine acetyltransferase 8 antibody, kat8 antibody, KAT8 antibody, Kat8 antibody
    背景

    Description: MYST1 (MYST histone acetyltransferase 1, MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone

    Aliases: MOF, KAT8, hMOF

    分子量
    53kDa
    基因ID
    84148
    HGNC
    84148
    UniProt
    Q9H7Z6
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