Tacrolimus (FK506) 抗体
FK506
适用: 化学剂
ELISA, WB
宿主: 小鼠
Monoclonal
FK1
unconjugated
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- 抗原
- Tacrolimus (FK506)
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适用
- 化学剂
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- Reacts with conjugated and non-conjugated FK-506 (Kd=10E-9M)
- 纯化方法
- Purified
- 免疫原
- FK-506 conjugated to bovine serum albumin.
- 克隆位点
- FK1
- 亚型
- IgM
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- 应用备注
- Working dilution: Optimal dilution should be determined by the end user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Dilute in PBS or medium which is identical to that used in the assay system.
- 储存条件
- -20 °C
- 储存方法
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Tacrolimus (FK506)
- 别名
- FK-506
- 物质类
- Chemical
- 背景
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FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/mL and depends on the patient's liver function, the nature of organ transplantation, and the time after transplantation.
Tacrolimus Fujimycin CAS : 109581-93-3 C44H69NO12 . H2O
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