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p53 抗体

TP53 适用: 人 ELISA (Capture) 宿主: 小鼠 Monoclonal B-F34 unconjugated
产品编号 ABIN1722440
发货至: 中国
  • 抗原 See all p53 (TP53) 抗体
    p53 (TP53) (Tumor Protein P53 (TP53))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This p53 antibody is un-conjugated
    应用范围
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    ELISA (Capture)
    特异性
    Reacts with wild type and mutant p53, the epitope is within residues 18-30 of human p53
    纯化方法
    Purified
    免疫原
    Recombinant p53 protein
    克隆位点
    B-F34
    亚型
    IgG2b
    Top Product
    Discover our top product TP53 Primary Antibody
  • 应用备注

    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    ELISA-C1 - 5 μg/mL

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    PBS, Sterile-filtered through 0.22 μm Carrier and Preservative free
    储存液
    Without preservative
    储存条件
    4 °C/-20 °C
    储存方法
    Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
    有效期
    6 months
  • 抗原
    p53 (TP53) (Tumor Protein P53 (TP53))
    别名
    p53 (TP53 产品)
    背景
    Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription.
    基因ID
    7157
    UniProt
    P04637
    途径
    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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