EPOR 抗体
(2 references)-
- 抗原 See all EPOR 抗体
- EPOR (Erythropoietin Receptor (EPOR))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This EPOR antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- 特异性
- Anti-human Epo-R
- 产品特性
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- 纯化方法
- Protein G
- 免疫原
- genetic immunisation with cDNA encoding the ECD of human Epo-R
- 克隆位点
- VP-2E8
- 亚型
- IgG1
- Top Product
- Discover our top product EPOR Primary Antibody
-
anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 301-450) antibodyEPOR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 470-504), (C-Term) antibodyEPOR 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB50846 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 45-244) antibodyEPOR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibodyEPOR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 274-508) antibodyEPOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 320-506) antibodyEPOR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 1-508) antibodyEPOR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (pTyr368) antibodyEPOR 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (pTyr426) antibodyEPOR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - 说明
-
Synonyms: Erythropoietin receptor
- 限制
- 仅限研究用
-
- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
-
-
: "Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. ..." in: British journal of haematology, Vol. 168, Issue 3, pp. 429-42, (2015) (PubMed).
: "The role of erythropoietin and erythropoiesis-stimulating agents in tumor progression." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 20, pp. 6373-80, (2011) (PubMed).
-
: "Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. ..." in: British journal of haematology, Vol. 168, Issue 3, pp. 429-42, (2015) (PubMed).
-
- 抗原
- EPOR (Erythropoietin Receptor (EPOR))
- 别名
- EPOR (EPOR 产品)
- 别名
- EPOR antibody, epor antibody, EPO-R antibody, erythropoietin receptor antibody, erythropoietin receptor L homeolog antibody, EPOR antibody, epor antibody, Epor antibody, epor.L antibody
- 背景
- Erythropoietin receptor (Epo-R) belongs to the cytokine receptor family and is a 507 amino acid type I transmembrane protein. EpoR pre-exists as dimers which changes the homodimerized state after binding of its 34 kDa ligand erythropoietin (Epo). Erythropoietin is the primary regulator of erythropoiesis, and promotes the survival, proliferation, and differentiation of erythroid progenitor cells. Both, Epo and Epo-R are essential for the production of red blood cells due to Epo exerts its function through the Epo receptor. The Epo-R is also expressed in many organs outside the bone marrow, suggesting that Epo is a pleiotropic anti-apoptotic factor. Signaling pathways have been shown to influence numerous cellular functions in normal and tumor cells, including proliferation, apoptosis, and drug resistance.
- UniProt
- P19235
- 途径
- JAK/STAT Signaling
-
