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- 抗原 See all CD81 抗体
- CD81
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适用
- 人
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD81 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- 特异性
- Anti-human CD81 (TAPA-1)
- 产品特性
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- 纯化方法
- Protein G
- 免疫原
- genetic immunisation with cDNA encoding human CD81
- 克隆位点
- QV-6A8-S3
- 亚型
- IgG2b
- Top Product
- Discover our top product CD81 Primary Antibody
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- 应用备注
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - 说明
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Synonyms: TAPA-1
- 限制
- 仅限研究用
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- 缓冲液
- PBS, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C
- 储存方法
- short term: 2 °C - 8 °C, long term: -20 °C
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A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
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A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." in: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
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- 抗原
- CD81
- 别名
- CD81 (CD81 产品)
- 别名
- Tapa-1 antibody, Tapa1 antibody, Tspan28 antibody, CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 molecule antibody, CD81 molecule b antibody, CD81 antigen antibody, Cd81 molecule antibody, CD81 antibody, cd81b antibody, Cd81 antibody
- 背景
- CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins. CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry.
- UniProt
- P60033
- 途径
- Inositol Metabolic Process, Hepatitis C
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