IGFBPL1 抗体 (AA 201-278)
(1 reference)-
- 抗原 See all IGFBPL1 products
- IGFBPL1 (Insulin-Like Growth Factor Binding Protein-Like 1 (IGFBPL1))
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抗原表位
- AA 201-278
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IGFBPL1 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human IGFBPL1
- 亚型
- IgG
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anti-Insulin-Like Growth Factor Binding Protein-Like 1 (IGFBPL1) (Internal Region) antibody
IGFBPL1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling." in: Clinical epigenetics, Vol. 12, Issue 1, pp. 22, (2021) (PubMed).
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: "Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling." in: Clinical epigenetics, Vol. 12, Issue 1, pp. 22, (2021) (PubMed).
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- 抗原
- IGFBPL1 (Insulin-Like Growth Factor Binding Protein-Like 1 (IGFBPL1))
- 别名
- IGFBPL1 (IGFBPL1 产品)
- 别名
- IGFBP-RP4 antibody, IGFBPRP4 antibody, bA113O24.1 antibody, 2810011G06Rik antibody, 2810453O06Rik antibody, IGFBPL antibody, insulin like growth factor binding protein like 1 antibody, insulin-like growth factor binding protein-like 1 antibody, IGFBPL1 antibody, Igfbpl1 antibody
- 背景
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Synonyms: bA113O24.1, IGFBP-related protein 10, IGFBP-RP4, IGFBPRP4, insulin-like growth factor binding protein related protein 4, insulin-like growth factor-binding protein-like 1, IBPL1_HUMAN, insulin-like growth factor-binding-related protein 4.
Background: IGFBPL1 is a secreted IGF (Insulin-like growth factor) binding protein that is known to contain an Ig-like C2-type (immunoglobulin-like) domain, an IGFBP N-terminal domain and a Kazal-like domain. IGF-binding proteins characteristically act to extend the half-life of IGFs and may influence the growth promoting effects of the IGFs. The interaction of IGFBPs with IGFs can affect cell surface receptors, specifically, IGFBPs may enhance or decrease a cells insulin sensitivity. IGFBPL1 has been found to be down-regulated in multiple tumors and thus may be a likely tumor suppressor candidate. Highly expressed in both brain and testis, IGFBPL1 is found at lower levels in the prostate, bladder and lung.
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