GLE1 抗体 (AA 611-698)
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- 抗原 See all GLE1 抗体
- GLE1 (GLE1 RNA Export Mediator (GLE1))
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抗原表位
- AA 611-698
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLE1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GLE1
- 亚型
- IgG
- Top Product
- Discover our top product GLE1 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- GLE1 (GLE1 RNA Export Mediator (GLE1))
- 别名
- GLE1 (GLE1 产品)
- 别名
- Dmel\\CG14749 antibody, GLE1 antibody, GLE1L antibody, LCCS antibody, LCCS1 antibody, hGLE1 antibody, Gle1l antibody, 4933405K21Rik antibody, AA553313 antibody, CG14749 gene product from transcript CG14749-RA antibody, nucleoporin GLE1 antibody, RNA export factor Gle1 antibody, GLE1, RNA export mediator antibody, GLE1 RNA export mediator antibody, GLE1 RNA export mediator (yeast) antibody, CG14749 antibody, CpipJ_CPIJ014147 antibody, SJAG_03847 antibody, GLE1 antibody, Gle1 antibody
- 背景
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Synonyms: GLE 1, GLE1, GLE1 like protein, GLE1 like RNA export mediator, GLE1 RNA export mediator homolog, GLE1 RNA export mediator like yeast, GLE1-like protein, GLE1_HUMAN, GLE1L, hGLE1, LCCS 1, LCCS, LCCS1, Nucleoporin GLE1.
Background: Protein transport across the nucleus is a selective, multi-step process involving several cytoplasmic factors that mediate protein passage through the nuclear pore complex (NPC). Gle1, also known as GLE1L, is a 698 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the Gle1 family. Expressed as two alternatively spliced isoforms, Gle1 associates with the NPC and is required for the transport of poly(A)-containing mRNAs from the nucleus to the cytoplasm. Defects in the gene encoding Gle1 are the cause of lethal congenital contracture syndrome type 1 (LCCS1) and lethal arthrogryposis with anterior horn cell disease (LAAHD), the former of which is characterized by early fetal hydrops and akinesia, micrognatia, pulmonary hypoplasia, pterygia and prenatal death, while the latter is associated with respiratory failure.
- 基因ID
- 2733
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