DYRK2 抗体 (AA 425-480)
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- 抗原 See all DYRK2 抗体
- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
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抗原表位
- AA 425-480
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DYRK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DYRK2
- 亚型
- IgG
- Top Product
- Discover our top product DYRK2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
- 别名
- DYRK2 (DYRK2 产品)
- 别名
- DYRK2 antibody, fc18c09 antibody, si:ch211-266a5.8 antibody, wu:fa09g03 antibody, wu:fc18c09 antibody, 1810038L18Rik antibody, dual specificity tyrosine phosphorylation regulated kinase 2 antibody, dual specificity tyrosine-phosphorylation-regulated kinase 2 antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 antibody, DYRK2 antibody, CpipJ_CPIJ014802 antibody, dyrk2 antibody, Dyrk2 antibody
- 背景
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Synonyms: 1810038L18Rik, Dual specicity tyrosine Y phosphorylation regulated kinase 2, Dual specicity tyrosine phosphorylation regulated kinase 2, Dual specicity tyrosine-phosphorylation-regulated kinase 2, DYRK2, DYRK2_HUMAN, EC 2.7.12.1, FLJ21217, FLJ21365.
Background: Dyrk is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis (13). Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation (1). Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4). Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions (4). Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome (1,5). Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4). Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland (1). The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively (4).
- 基因ID
- 8445
- 途径
- Regulation of Carbohydrate Metabolic Process
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