BORA 抗体 (AA 31-130)
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- 抗原 See all BORA 抗体
- BORA (Protein Aurora Borealis (BORA))
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抗原表位
- AA 31-130
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BORA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BORA
- 亚型
- IgG
- Top Product
- Discover our top product BORA Primary Antibody
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anti-Protein Aurora Borealis (BORA) (AA 178-312) antibody
BORA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Aurora Borealis (BORA) (C-Term) antibodyBORA 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Aurora Borealis (BORA) (AA 320-619) antibodyBORA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Aurora Borealis (BORA) (C-Term) antibodyBORA 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Protein Aurora Borealis (BORA) (N-Term) antibodyBORA 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- BORA (Protein Aurora Borealis (BORA))
- 别名
- BORA (BORA 产品)
- 别名
- CG6897 antibody, Dmel\\CG6897 antibody, zgc:101616 antibody, C13orf34 antibody, 6720463M24Rik antibody, AI317232 antibody, RGD1309522 antibody, c13orf34 antibody, C12H13orf34 antibody, aurora borealis antibody, bora, aurora kinase A activator antibody, protein aurora borealis antibody, bora, aurora kinase A activator S homeolog antibody, bora antibody, Tsp_06066 antibody, Bora antibody, BORA antibody, bora.S antibody
- 背景
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Synonyms: Aurora borealis, bora, BORA_HUMAN, C13orf34, Chromosome 13 open reading frame 34, FLJ22624, HsBora, Protein aurora borealis, RP11-342J4.2.
Background: Aurora related kinase-1 (ARK-1) is a centrosome-associated serine/threonine kinase that regulates centrosome separation, bipolar spindle assembly and chromosome segregation during mitosis. Bora (protein aurora borealis) is a 559 amino acid protein that activates ARK-1. Bora is localized to the nucleus until mitosis is initiated, when it then translocates to the cytoplasm. This translocation is dependent on activated Cdc2, which releases Bora to bind and activate ARK-1 in the cytoplasm. Plk (polo-like kinase) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation on its N-terminus by ARK-1. It is through this mechanism that Bora and ARK-1 control cellular mitotic entry. Downregulation of the gene encoding Bora results in multipolar spindles in mitosis, a phenomenon that is also observed when ARK-1 function is blocked.
- 基因ID
- 79866
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