BLM 抗体 (AA 1201-1417)
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- 抗原 See all BLM 抗体
- BLM (Bloom Syndrome RecQ Like Helicase (BLM))
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抗原表位
- AA 1201-1417
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BLM antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BLM/Blooms Syndrome Protein Blm
- 亚型
- IgG
- Top Product
- Discover our top product BLM Primary Antibody
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anti-Bloom Syndrome RecQ Like Helicase (BLM) (C-Term) antibody
BLM 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (pThr99) antibodyBLM 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1196-1295) antibodyBLM 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (N-Term) antibodyBLM 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1196-1295) antibodyBLM 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Bloom Syndrome RecQ Like Helicase (BLM) (AA 1054-1082), (C-Term) antibodyBLM 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB25943 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- BLM (Bloom Syndrome RecQ Like Helicase (BLM))
- 别名
- BLM/Blooms Syndrome Protein Blm (BLM 产品)
- 别名
- BS antibody, RECQ2 antibody, RECQL2 antibody, RECQL3 antibody, blm-A antibody, xBLM antibody, ORF1 antibody, Bloom syndrome RecQ like helicase antibody, Bloom syndrome RecQ like helicase S homeolog antibody, Bloom syndrome, RecQ like helicase antibody, BLM antibody, blm.S antibody, Blm antibody
- 背景
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Synonyms: BLM, BLM_HUMAN, Bloom Syndrome, Bloom syndrome protein, Bloom syndrome RecQ helicase like, BS, DNA Helicase, DNA helicase RecQ like type 2, MGC126616, MGC131618, MGC131620, RECQ 2, RECQ like, RecQ like type 2, RecQ protein like 3, RecQ Protein-like 3, RECQ-2, RECQ-Like, RecQ-like type 2, RECQ2, RECQL 2, RECQL 3, RECQL-2, RECQL-3, RECQL2, RECQL3, type 2.
Background: Bloom?s syndrome is an autosomal recessive disorder characterized by pre- and post-natal growth deficiencies, sun sensitivity, immunodeficiency and a predisposition to various cancers. The gene responsible for Bloom?s syndrome, BLM, encodes a protein homologous to the RecQ helicase of E. coli and is mutated in most Bloom?s syndrome patients. One characteristic of Bloom?s syndrome is an increased frequency of sister chromatid exchange (SCE). BLM has been shown to unwind G4 DNA, and a failure of this function is thought to be responsible for the increased rate of SCE. BLM is known to be translocated to the nucleus, where its ATPase activity is stimulated by both single- and double-stranded DNA. Mutations in the yeast SGS1, a homolog of BLM, are known to cause mitotic hyperrecombination similiar to that observed in Bloom?s cells.
- 基因ID
- 641
- 途径
- DNA Damage Repair
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