ANAPC11 抗体 (AA 1-84)
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- 抗原 See all ANAPC11 抗体
- ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))
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抗原表位
- AA 1-84
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANAPC11 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 预测反应
- Human,Mouse,Rat,Dog,Sheep,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human APC11
- 亚型
- IgG
- Top Product
- Discover our top product ANAPC11 Primary Antibody
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anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) antibody
ANAPC11 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) (AA 1-196) antibodyANAPC11 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6F1H6 unconjugated
anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) (AA 1-54) antibodyANAPC11 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1B4-1A4 unconjugated
anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) antibodyANAPC11 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1B5 unconjugated
anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) (AA 56-94) antibodyANAPC11 适用: 人 WB 宿主: 兔 Polyclonal RB56253 unconjugated
anti-Anaphase Promoting Complex Subunit 11 (ANAPC11) (Internal Region) antibodyVerified ANAPC11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))
- 别名
- APC11 (ANAPC11 产品)
- 别名
- APC11 antibody, Apc11p antibody, anapc11 antibody, RGD1561880 antibody, F10A16.17 antibody, F10A16_17 antibody, anaphase-promoting complex/cyclosome 11 antibody, DDBDRAFT_0187183 antibody, DDBDRAFT_0231277 antibody, DDB_0187183 antibody, DDB_0231277 antibody, 1110011I19Rik antibody, R75218 antibody, zgc:153671 antibody, si:dkey-237i9.4 antibody, anaphase promoting complex subunit 11 antibody, anaphase promoting complex subunit 11 L homeolog antibody, anaphase-promoting complex/cyclosome 11 antibody, anaphase-promoting complex subunit Apc11 antibody, ubiquitin-protein ligase Anaphase Promoting Complex antibody, hypothetical protein antibody, predicted protein antibody, anaphase-promoting complex subunit 11 antibody, APC11 anaphase promoting complex subunit 11 homolog (yeast) antibody, ANAPC11 antibody, anapc11.L antibody, anapc11 antibody, Anapc11 antibody, APC11 antibody, apc11 antibody, CAALFM_CR10610CA antibody, LOC9320604 antibody, LOC692923 antibody
- 背景
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Synonyms: ANAPC 11, ANAPC11, Anaphase promoting complex subunit 11, Anaphase promoting complex subunit 11 homolog yeast, Anaphase promoting complex subunit 11 homolog, Anaphase-promoting complex subunit 11, Apc 11, Apc 11p, APC11 anaphase promoting complex subunit 11 homolog yeast, APC11 anaphase promoting complex subunit 11 homolog, APC11, APC11_HUMAN, Apc11p, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, Hepatocellular carcinoma-associated RING finger protein, HSPC 214, HSPC214, MGC882, Yeast APC 11 homolog, Yeast APC11 homolog.
Background: Comprising more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to APC and activates APC?s cyclin-ubiquitination activity. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC, thus preventing APC activation. APC11 is a RING-H2 finger protein that allows for the synthesis of multiubiquitin chains in the presence of Ubiquitin carrier protein 4 (Ubc4) and ubiquitin conjugating enzyme (E2). In addition, a heterodimeric complex of either Ubc4 or UbcH10 with APC11 and APC2 catalyzes the ubiquitination of human securin and cyclin B1.
- 基因ID
- 51529
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