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MAML1 抗体 (AA 401-500)

MAML1 适用: 小鸡 ELISA, WB, IHC (p), IHC (fro), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1714470
发货至: 中国
  • 抗原 See all MAML1 抗体
    MAML1 (Mastermind-Like 1 (MAML1))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    适用
    • 30
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    小鸡
    宿主
    • 28
    • 1
    • 1
    克隆类型
    • 30
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    This MAML1 antibody is un-conjugated
    应用范围
    • 24
    • 20
    • 13
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鸡
    预测反应
    Human,Mouse,Rat,Dog,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MAML1
    亚型
    IgG
    Top Product
    Discover our top product MAML1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Wu, Yu, Zhang, Zhang: "Cardioprotective effect of Notch signaling on the development of myocardial infarction complicated by diabetes mellitus." in: Experimental and therapeutic medicine, Vol. 14, Issue 4, pp. 3447-3454, (2017) (PubMed).

  • 抗原
    MAML1 (Mastermind-Like 1 (MAML1))
    别名
    MAML1 (MAML1 产品)
    别名
    mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
    背景

    Synonyms: Mam-1, Mam1, MAML 1, MAML 1, Maml1, MAML1_HUMAN, Mastermind like 1, Mastermind-like protein 1, mKIAA0200.

    Background: Notch receptors are involved in cell-fate determination in organisms as diverse as flies, frogs, and humans (1). The 'mastermind' gene has been identified in multiple genetic screens for modifiers of Notch mutations in Drosophila melanogaster (2). In Drosophila, loss-of-function mutations of Notch produce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentiate to neural cells (2). The human homolog, mastermind-like 1 (Mam1), localizes to nuclear bodies (2-4). Mam1 binds to the ankyrin repeat domain of all four mammalian Notch receptors, forms a DNA-binding complex with ICN and RBP-Jk, and amplifies Notch-induced transcription of Hes1 (2). Mam1 is an essential component of the transcriptional apparatus of Notch signaling (5). The gene which encodes Mam1 maps to human chromosome 5 (4).

    基因ID
    9794
    途径
    Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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