EIF2A 抗体 (pSer52)
(3 references)-
- 抗原 See all EIF2A 抗体
- EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
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抗原表位
- pSer52
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Cow
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human eIF2 alpha subunit 1 around the phosphorylation site of Ser52 [EL(p-S)RR]
- 亚型
- IgG
- Top Product
- Discover our top product EIF2A Primary Antibody
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anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 448-576) antibody
EIF2A 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3A7B11 unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 448-576) antibodyEIF2A 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A7A8 unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibodyEIF2A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) antibodyEIF2A 适用: 人, 小鼠, 大鼠, 猴, 犬, Cow, 兔, 豚鼠, Hamster, Pig, 绵羊 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 437-465) antibodyEIF2A 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 1-100) antibodyEIF2A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (Center) antibodyEIF2A 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (Ser326) antibodyEIF2A 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (AA 504-553) antibodyEIF2A 适用: 人, 猴, 犬, Cow, 马, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (C-Term) antibodyEIF2A 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "miR-211 Plays a Critical Role in Cnidium officinale Makino Extract-Induced, ROS/ER Stress-Mediated Apoptosis in U937 and U266 Cells." in: International journal of molecular sciences, Vol. 19, Issue 3, (2018) (PubMed).
: "A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure." in: Nature communications, Vol. 8, Issue 1, pp. 133, (2017) (PubMed).
: "Sustained endoplasmic reticulum stress inhibits hepatocyte proliferation via downregulation of c-Met expression." in: Molecular and cellular biochemistry, Vol. 389, Issue 1-2, pp. 151-8, (2014) (PubMed).
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: "miR-211 Plays a Critical Role in Cnidium officinale Makino Extract-Induced, ROS/ER Stress-Mediated Apoptosis in U937 and U266 Cells." in: International journal of molecular sciences, Vol. 19, Issue 3, (2018) (PubMed).
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- 抗原
- EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))
- 别名
- eIF2 alpha (EIF2A 产品)
- 背景
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Synonyms: EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, EIF2S1
Background: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 4S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 6S ribosomal subunit to form the 8S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
- 基因ID
- 1965
- UniProt
- P05198
- 途径
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
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