KNDC1 抗体 (AA 1601-1749)
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- 抗原 See all KNDC1 抗体
- KNDC1 (Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1 (KNDC1))
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抗原表位
- AA 1601-1749
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KNDC1 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunocytochemistry (ICC)
- 预测反应
- Human,Mouse,Rat,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KNDC1
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- KNDC1 (Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1 (KNDC1))
- 别名
- KNDC1 (KNDC1 产品)
- 别名
- C10orf23 antibody, RASGEF2 antibody, bB439H18.3 antibody, 2410012C07Rik antibody, B830014K08Rik antibody, VKIND antibody, very-kind antibody, RGD1565261 antibody, kinase non-catalytic C-lobe domain containing 1 antibody, kinase non-catalytic C-lobe domain (KIND) containing 1 antibody, protein very KIND antibody, KNDC1 antibody, Kndc1 antibody, LOC536342 antibody
- 背景
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Synonyms: Cerebral protein 9, FLJ25027, hucep-9, KIAA1768, Kinase non-catalytic C-lobe domain-containing protein 1, KIND domain-containing protein 1, KNDC1, Protein very KIND, Ras-GEF domain-containing family member 2, RASGEF2, VKIND, VKIND_HUMAN, bB439H18.3, C10orf23.
Background: KNDC1 is a 1,749 amino acid protein that contains two KIND domains and an N-terminal Ras-GEF domain. Expressed in the cerebral cortex, KNDC1 is a likely guanine nucleotide exchange factor (GEF). Existing as six alternatively spliced isoforms, the gene encoding KNDC1 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
- 基因ID
- 85442
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