FMR1 抗体 (pSer500)
-
- 抗原 See all FMR1 抗体
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
-
抗原表位
- pSer500
-
适用
- 人, 小鼠, 大鼠, 斑马鱼
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FMR1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠, 斑马鱼
- 预测反应
- Dog,Cow,Sheep,Pig,Chicken,Rabbit,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500
- 亚型
- IgG
- Top Product
- Discover our top product FMR1 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- FMR1 (Fragile X Mental Retardation 1 (FMR1))
- 别名
- FMRP (FMR1 产品)
- 背景
-
Synonyms: POF, FMRP, POF1, FRAXA, Fragile X mental retardation protein 1, Protein FMR-1, FMR1
Background: Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
- 基因ID
- 2332
- UniProt
- Q06787
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
-