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- 抗原 See all NET1 抗体
- NET1 (Neuroepithelial Cell Transforming 1 (NET1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NET1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NET1
- 亚型
- IgG
- Top Product
- Discover our top product NET1 Primary Antibody
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anti-Neuroepithelial Cell Transforming 1 (NET1) (AA 1-300) antibody
NET1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuroepithelial Cell Transforming 1 (NET1) (AA 1-542) antibodyNET1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Neuroepithelial Cell Transforming 1 (NET1) (C-Term) antibodyNET1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuroepithelial Cell Transforming 1 (NET1) (C-Term) antibodyVerified NET1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Neuroepithelial Cell Transforming 1 (NET1) (AA 356-385) antibodyNET1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB30330 unconjugated
anti-Neuroepithelial Cell Transforming 1 (NET1) (AA 501-596) antibodyNET1 适用: 人, 小鼠 WB, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuroepithelial Cell Transforming 1 (NET1) antibodyNET1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Neuroepithelial Cell Transforming 1 (NET1) (AA 1-542) antibodyNET1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neuroepithelial Cell Transforming 1 (NET1) (AA 72-121) antibodyNET1 适用: 人, 大鼠, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- NET1 (Neuroepithelial Cell Transforming 1 (NET1))
- 别名
- NET1 (NET1 产品)
- 别名
- arhgef8 antibody, net1a antibody, xNET1 antibody, DKFZp459I0423 antibody, NET1 antibody, ARHGEF8 antibody, NET1A antibody, 0610025H04Rik antibody, 9530071N24Rik antibody, AI604373 antibody, AU015857 antibody, Net1a antibody, mNET1 antibody, wu:fb13g03 antibody, wu:fb25c11 antibody, zgc:92121 antibody, neuroepithelial cell transforming 1 antibody, neuroepithelial cell-transforming gene 1 protein antibody, neuroepithelial cell transforming 1 L homeolog antibody, neuroepithelial cell transforming gene 1 antibody, net1 antibody, EDI_348570 antibody, NET1 antibody, Net1 antibody, net1.L antibody
- 背景
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Synonyms: NAT1, NET, NET, NET1, Norepinephrine transporter, SLC6A2, SLC6A5, SLC6A5, Sodium dependent noradrenaline transporter, Solute carrier family 6 neurotransmitter transporter norepinephrine member 5, Solute carrier family 6 member 2, Solute carrier family 6 member 2.
Background: Catecholamine, a term used for the hormone adrenaline and its sequentially hydroxylated form noradrenaline, is involved in fight or flight responses. Noradrenaline is released from the post ganglionic sympathetic nerve endings and exerts its effects locally in the immediate vicinity of its release. In the CNS, noradrenaline is involved in a number of physiological responses including mood, sleep regulation, alertness and arousal, both cognitive and non-cognitive expression of behaviors, and control of the endocrine and autonomic nervous systems. Peripherally, noradrenaline is present in sympathetic nerve endings and has full control of the sympathetic nervous system. Noradrenaline released from pre-synaptic nerve terminals is reabsorbed (70-90 % ) by noradrenaline transporters and its biological effects are terminated. The noradrenaline transport via noradrenaline transporters is an active, Na+/Cl- dependent transport process mediated by noradrenaline transporters. Noradrenaline transporters constitute the primary mechanism for inactivation of synaptically released noradrenaline, are targets for multiple antidepressants and psychostimulants, and are deficient in affective and autonomic disorders. In rat brain, noradrenaline transporter is expressed in noradrenergic neuronal somata, axons and dendrites, and hippocampus and cortex, but is absent from epinephrine- and dopamine-containing neurons. At least 13 genetic variations have been reported in the noradrenaline transporter protein that affect noradrenaline re-uptake and concentrations in cerebrospinal fluid in humans. The association between these genetic variations in noradrenaline transporters and several psychiatric and cardiovascular disorders is just emerging. Recently, a single amino acid mutation (hNET-A457P) showed deficiency in noradrenaline transport in an orthostatic intolerance patient. Noradrenaline transporter protein consists of 617 amino acids and has 12 trans-membrane domains.
- 基因ID
- 6530
- 途径
- Neurotrophin Signaling Pathway
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