HOOK1 抗体 (AA 551-650)
(1 reference)-
- 抗原 See all HOOK1 抗体
- HOOK1 (Hook Homolog 1 (HOOK1))
-
抗原表位
- AA 551-650
-
适用
- 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HOOK1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HOOK1
- 亚型
- IgG
- Top Product
- Discover our top product HOOK1 Primary Antibody
-
anti-Hook Homolog 1 (HOOK1) (AA 1-728) antibody
HOOK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hook Homolog 1 (HOOK1) (AA 632-728) antibodyHOOK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Hook Homolog 1 (HOOK1) (AA 301-600) antibodyHOOK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hook Homolog 1 (HOOK1) (AA 632-728) antibodyHOOK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hook Homolog 1 (HOOK1) (AA 1-728) antibodyHOOK1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hook Homolog 1 (HOOK1) (AA 464-513) antibodyHOOK1 适用: 人, 小鼠, 大鼠, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Hook Homolog 1 (HOOK1) (AA 632-729) antibodyHOOK1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Hook Homolog 1 (HOOK1) (AA 489-728) antibodyHOOK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
-
: "Ccdc181 is a microtubule-binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia." in: European journal of cell biology, Vol. 96, Issue 3, pp. 276-288, (2018) (PubMed).
-
: "Ccdc181 is a microtubule-binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia." in: European journal of cell biology, Vol. 96, Issue 3, pp. 276-288, (2018) (PubMed).
-
- 抗原
- HOOK1 (Hook Homolog 1 (HOOK1))
- 别名
- HOOK1 (HOOK1 产品)
- 别名
- si:dkey-183n20.14 antibody, A930033L17Rik antibody, azh antibody, HK1 antibody, HOOK1 antibody, hook microtubule tethering protein 1 antibody, hook microtubule-tethering protein 1 antibody, HOOK1 antibody, hook1 antibody, Hook1 antibody
- 背景
-
Synonyms: A930033L17Rik, Abnormal spermatozoon head shape, azh, h-hook1, hHK1, HK1, HOOK 1, Hook homolog 1 Drosophila, Hook1, HOOK1_HUMAN, MGC10642, OTTHUMP00000010548, OTTMUSP00000008480, Protein Hook homolog 1, RP23-80B16.4.
Background: Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.
- 基因ID
- 51361
- 途径
- SARS-CoV-2 Protein Interactome
-
