XPO1 抗体 (AA 701-800)
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- 抗原 See all XPO1 抗体
- XPO1 (Exportin 1 (XPO1))
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抗原表位
- AA 701-800
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XPO1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Exportin 1/CRM1
- 亚型
- IgG
- Top Product
- Discover our top product XPO1 Primary Antibody
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anti-Exportin 1 (XPO1) (AA 966-1071) antibody
XPO1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 625-845) antibodyXPO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (C-Term) antibodyXPO1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 兔, Pig, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (acLys568) antibodyXPO1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 917-1071) antibodyXPO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) antibodyXPO1 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 9F2 unconjugated Recombinant Antibody
anti-Exportin 1 (XPO1) (acLys568) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 966-1071) antibodyXPO1 适用: 人 WB, IHC (p), FACS, ICC, IHC (fro) 宿主: 小鼠 Monoclonal 5G3 unconjugated
anti-Exportin 1 (XPO1) (AA 817-846), (C-Term) antibodyXPO1 适用: 人 IHC (p), FACS 宿主: 兔 Polyclonal RB19972 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- XPO1 (Exportin 1 (XPO1))
- 别名
- Exportin 1/CRM1 (XPO1 产品)
- 背景
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Synonyms: emb, CRM1, exp1, Exportin-1, Chromosome region maintenance 1 protein homolog, XPO1
Background: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus. Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins. Involved in HTLV-1 Rex multimerization.
- 基因ID
- 7514
- UniProt
- O14980
- 途径
- M Phase
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