DOCK4 抗体 (AA 1001-1100)
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- 抗原 See all DOCK4 抗体
- DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))
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抗原表位
- AA 1001-1100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOCK4 antibody is un-conjugated
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应用范围
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DOCK4
- 亚型
- IgG
- Top Product
- Discover our top product DOCK4 Primary Antibody
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anti-Dedicator of Cytokinesis 4 (DOCK4) (AA 1867-1966) antibody
DOCK4 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3E7 unconjugated
anti-Dedicator of Cytokinesis 4 (DOCK4) (AA 1867-1966) antibodyDOCK4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Dedicator of Cytokinesis 4 (DOCK4) (AA 1-300) antibodyDOCK4 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 4 (DOCK4) (AA 1867-1966) antibodyDOCK4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Dedicator of Cytokinesis 4 (DOCK4) (AA 150-450) antibodyDOCK4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))
- 别名
- DOCK4 (DOCK4 产品)
- 别名
- DOCK4 antibody, 5330406C03 antibody, 6330411N01Rik antibody, AF263288 antibody, C030023J22 antibody, mKIAA0716 antibody, dedicator of cytokinesis 4 antibody, DOCK4 antibody, NAEGRDRAFT_81257 antibody, Dock4 antibody
- 背景
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Synonyms: Dedicator of cytokinesis protein 4, Dock4, DOCK4_HUMAN, KIAA0716.
Background: DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.
- 基因ID
- 9732
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