BOP1 抗体 (AA 201-300)
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- 抗原 See all BOP1 抗体
- BOP1 (Block of Proliferation 1 (BOP1))
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抗原表位
- AA 201-300
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BOP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BOP1
- 亚型
- IgG
- Top Product
- Discover our top product BOP1 Primary Antibody
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anti-Block of Proliferation 1 (BOP1) (AA 600-680) antibody
BOP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (AA 35-84) antibodyBOP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (N-Term) antibodyBOP1 适用: 人, 小鼠, 大鼠, 马, Pig, 犬, Bat, Drosophila melanogaster, Insect, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (N-Term) antibodyBOP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (N-Term) antibodyBOP1 适用: 人, 大鼠, 马, Pig, 犬, Cow, 豚鼠, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Block of Proliferation 1 (BOP1) (N-Term) antibodyBOP1 适用: 人, 小鼠, 大鼠, 马, Pig, 犬, 兔, Saccharomyces cerevisiae, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- BOP1 (Block of Proliferation 1 (BOP1))
- 别名
- BOP1 (BOP1 产品)
- 别名
- AU020183 antibody, AW146150 antibody, D18861 antibody, Erb1p antibody, Kiaa0124 antibody, mKIAA0124 antibody, bop1-B antibody, id:ibd1283 antibody, si:ch211-251g8.2 antibody, si:ch211-251g8.4 antibody, zgc:154135 antibody, MCG5033 antibody, bop1-a antibody, bop1-b antibody, Block of proliferation 1 antibody, block of proliferation 1 antibody, block of proliferation 1 L homeolog antibody, block of proliferation 1 S homeolog antibody, GL50803_8035 antibody, Mbre_bop1 antibody, Bop1 antibody, bop1.L antibody, BOP1 antibody, bop1 antibody, bop1.S antibody
- 背景
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Synonyms: AU020183, AW146150, Block of proliferation 1, Block of proliferation 1 protein, Bop1, Bop1 block of proliferation 1, BOP1_HUMAN, D18861, Erb1p, Kiaa0124, MGC109114, mKIAA0124, Ribosome biogenesis protein BOP1.
Background: Predominantly localized to the nucleolus, BOP1 (Block of proliferation 1 protein) is a 746 amino acid highly conserved non-ribosomal protein that is involved in ribosome biogenesis. Truncation of the amino terminus of BOP1 leads to cell growth arrest in the G1 phase and specific inhibition of 28S and 5.8S rRNA synthesis, as well as a deficit in the cytosolic 60S ribosomal subunit. This suggests that BOP1 is involved in the formation of mature rRNAs and in the biogenesis of the 60S ribosomal subunit. BOP1 physically interacts with pescadillo (a protein involved in cell proliferation) and enables efficient incorporation of pescadillo into the nucleolar preribosomal complexes, thereby affecting rRNA maturation and the cell cycle. The BOP1-pescadillo complex is also necessary for biogenesis of 60S ribosomal subunits. Deregulation of BOP1 may lead to colorectal tumorigenesis.
- 基因ID
- 23246
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