ASAH1 抗体 (AA 301-395)
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- 抗原 See all ASAH1 抗体
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
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抗原表位
- AA 301-395
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ASAH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Acid ceramidase subunit beta
- 亚型
- IgG
- Top Product
- Discover our top product ASAH1 Primary Antibody
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anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 144-395) antibody
ASAH1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 25-124) antibodyASAH1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 146-395) antibodyASAH1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 25-125) antibodyASAH1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 25-125) antibodyASAH1 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 22-395) antibodyASAH1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 146-395) antibodyASAH1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 1-395) antibodyASAH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (N-Term) antibodyASAH1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1) (AA 140-389) antibodyASAH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
- 别名
- ASAH1 (ASAH1 产品)
- 背景
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Synonyms: AC, ACDase, Acid CDase, Acid ceramidase, Acid ceramidase precursor, Acid ceramidase subunit beta, Acylsphingosine deacylase, ASAH 1, ASAH, ASAH1, ASAH1_HUMAN, FLJ21558, FLJ22079, N acylsphingosine amidohydrolase acid ceramidase 1, N acylsphingosine amidohydrolase 1, N acylsphingosine amidohydrolase, N-acylsphingosine amidohydrolase, PHP, PHP32, Putative 32 kDa heart protein.
Background: Acid ceramidase catalyzes the degradation of ceramide in normal tissues, and deficiency leads to accumulation of ceramide in tissues, a hallmark of Farber disease. Effected individuals experience early onset joint problems and neurological problems, owing to mutations in the acid ceramidase gene. Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma. In addition to ceramide hydrolysis, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates. Interestingly, pH regulates which reaction is favored, for hydrolysis the pH optimum is 4.5, whereas for the reverse reaction favors a pH of 5.5, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism.
- 基因ID
- 427
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