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TRRAP 抗体 (AA 3401-3600)

TRRAP 适用: 人, 大鼠, 非洲爪蟾 ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1714098
发货至: 中国
  • 抗原 See all TRRAP 抗体
    TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))
    抗原表位
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3401-3600
    适用
    • 12
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 非洲爪蟾
    宿主
    • 10
    • 2
    • 2
    克隆类型
    • 12
    • 2
    多克隆
    标记
    • 14
    This TRRAP antibody is un-conjugated
    应用范围
    • 11
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 大鼠, 非洲爪蟾
    预测反应
    Mouse,Dog,Sheep,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TRRAP
    亚型
    IgG
    Top Product
    Discover our top product TRRAP Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))
    别名
    TRRAP (TRRAP 产品)
    别名
    PAF350/400 antibody, PAF400 antibody, STAF40 antibody, TR-AP antibody, Tra1 antibody, AI481500 antibody, TRRAP antibody, trrap antibody, transformation/transcription domain associated protein antibody, phosphotransferases/inositol or phosphatidylinositol kinase antibody, transcription-associated protein 1 antibody, transformation/transcription domain-associated protein antibody, TRRAP antibody, AT4G36080 antibody, LOC5577036 antibody, Trrap antibody, trrap antibody, LOC100637779 antibody
    背景

    Synonyms: 350/400 kDa PCAF associated factor, FLJ10671, PAF 350/400, PAF 400, PAF350/400, PAF400, STAF 40, STAF40, TR AP, Tra 1, Tra1, Tra1 homolog, Transactivation / transformation domain associated protein, Transactivation/transformation domain associated protein, Transformation/transcription domain associated protein, TRAP, TRRAP_HUMAN.

    Background: The transcription factors c-Myc and E2F are involved in regulating cell cycle progression. Overexpression of c-Myc in certain cell types induces noncycling cells to enter the cell cycle via a mechanism involving E2F-1 (1). E2F-1 is thought to regulate c-Myc expression via interactions with the retinoblastoma protein (2). TRRAP (for transformation/transcription domain-associated protein) interacts specifically with both c-Myc and E2F-1. Expression of trans-activated mutant TRRAP inhibits the oncogenic transformation of both c-Myc and E2F-1, suggesting that TRRAP is required for these oncogenic transcription factor pathways (3). TRRAP shares homology with the ATM/PI 3-kinase family, and it is highly conserved in evolution (4,5).

    基因ID
    8295
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