TRRAP 抗体 (AA 3401-3600)
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- 抗原 See all TRRAP 抗体
- TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))
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抗原表位
- AA 3401-3600
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适用
- 人, 大鼠, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRRAP antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠, 非洲爪蟾
- 预测反应
- Mouse,Dog,Sheep,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TRRAP
- 亚型
- IgG
- Top Product
- Discover our top product TRRAP Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))
- 别名
- TRRAP (TRRAP 产品)
- 别名
- PAF350/400 antibody, PAF400 antibody, STAF40 antibody, TR-AP antibody, Tra1 antibody, AI481500 antibody, TRRAP antibody, trrap antibody, transformation/transcription domain associated protein antibody, phosphotransferases/inositol or phosphatidylinositol kinase antibody, transcription-associated protein 1 antibody, transformation/transcription domain-associated protein antibody, TRRAP antibody, AT4G36080 antibody, LOC5577036 antibody, Trrap antibody, trrap antibody, LOC100637779 antibody
- 背景
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Synonyms: 350/400 kDa PCAF associated factor, FLJ10671, PAF 350/400, PAF 400, PAF350/400, PAF400, STAF 40, STAF40, TR AP, Tra 1, Tra1, Tra1 homolog, Transactivation / transformation domain associated protein, Transactivation/transformation domain associated protein, Transformation/transcription domain associated protein, TRAP, TRRAP_HUMAN.
Background: The transcription factors c-Myc and E2F are involved in regulating cell cycle progression. Overexpression of c-Myc in certain cell types induces noncycling cells to enter the cell cycle via a mechanism involving E2F-1 (1). E2F-1 is thought to regulate c-Myc expression via interactions with the retinoblastoma protein (2). TRRAP (for transformation/transcription domain-associated protein) interacts specifically with both c-Myc and E2F-1. Expression of trans-activated mutant TRRAP inhibits the oncogenic transformation of both c-Myc and E2F-1, suggesting that TRRAP is required for these oncogenic transcription factor pathways (3). TRRAP shares homology with the ATM/PI 3-kinase family, and it is highly conserved in evolution (4,5).
- 基因ID
- 8295
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