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GSK3 alpha/beta 抗体 (AA 151-250)

GSK3a/b 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1714094
发货至: 中国
  • 抗原 See all GSK3 alpha/beta (GSK3a/b) products
    GSK3 alpha/beta (GSK3a/b) (Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))
    抗原表位
    • 21
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    适用
    • 33
    • 33
    • 33
    • 4
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 32
    • 1
    克隆类型
    • 30
    • 3
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GSK3 alpha/beta antibody is un-conjugated
    应用范围
    • 27
    • 14
    • 14
    • 13
    • 8
    • 8
    • 7
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GSK3 Alpha + Beta
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Freese, Reinhardt, Hefner, Unger, Kirkpatrick, Endres: "A novel blood-brain barrier co-culture system for drug targeting of Alzheimer's disease: establishment by using acitretin as a model drug." in: PLoS ONE, Vol. 9, Issue 3, pp. e91003, (2014) (PubMed).

  • 抗原
    GSK3 alpha/beta (GSK3a/b) (Glycogen Synthase Kinase 3 alpha/beta (GSK3a/b))
    别名
    GSK3 Alpha + Beta (GSK3a/b 产品)
    背景

    Synonyms: Gsk3a, GSK 3 alpha, GSK-3 alpha, GSK3 alpha, Glycogen synthase kinase-3 alpha, GSK 3 alpha, DKFZp686D0638, GSK 3A, GSK3A, GSK3alpha, GSK3A_HUMAN, Glycogen synthase kinase 3 alpha, Serine/threonine-protein kinase GSK3A, Glycogen synthase kinase 3 beta, GSK 3 beta, GSK 3B, GSK3B, GSK3B protein, GSK3beta isoform, GSK3 beta, Glycogen synthase kinase-3 beta, GSK-3 beta, GSK3B_HUMAN, Serine/threonine-protein kinase GSK3B.

    Background: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].

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