FANCA 抗体 (AA 461-560)
-
- 抗原 See all FANCA 抗体
- FANCA (Fanconi Anemia Group A Protein (FANCA))
-
抗原表位
- AA 461-560
-
适用
- 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FANCA antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FANCA
- 亚型
- IgG
- Top Product
- Discover our top product FANCA Primary Antibody
-
anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibody
FANCA 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 995-1009) antibodyFANCA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-297) antibodyFANCA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1121-1170), (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 609-813) antibodyFANCA 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) antibodyFANCA 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 71-120) antibodyFANCA 适用: 人, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibodyFANCA 适用: 人 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-275) antibodyFANCA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- FANCA (Fanconi Anemia Group A Protein (FANCA))
- 别名
- FANCA (FANCA 产品)
- 别名
- FA antibody, FA-H antibody, FA1 antibody, FAA antibody, FACA antibody, FAH antibody, FANCH antibody, AW208693 antibody, Fanconi anemia complementation group A antibody, Fanconi anemia, complementation group A antibody, FANCA antibody, Fanca antibody
- 背景
-
Synonyms: FA 1, FA, FA H, FA1, FAA, FACA, FAH, Fanca, FANCA_HUMAN, FANCH, Fanconi anemia complementation group A, Fanconi anemia complementation group H, Fanconi anemia group A protein, Fanconi anemia type 1, MGC75158, Protein FACA.
Background: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromosomal instability. At the cellular level, FA is characterized by spontaneous chromosomal breakage and a unique hypersensitivity to DNA cross-linking agents. At least eight complementation groups (A-G) have been identified and six FA genes (for subtypes A, C, D2, E, F and G) have been cloned. The FA proteins lack sequence homologies or motifs that could point to a molecular function. The cellular accumulation of FA proteins, including FANCA and FANCG, is subject to regulation by TNF alpha signaling. Phosphorylation of FANC (Fanconi anemia complementation group) proteins is thought to be important for the function of the FA pathway. FANCA, also known as FACA and FANCH, associates with the Brm-related gene 1 (BRG1) product, a subunit of the SWI/SNF complex which remodels chromatin structure through a DNA-dependent ATPase activity. FANCA is mainly expressed in lymphoid tissues, testis and ovary. The amino-terminal region of the FANCA protein is required for FANCG binding, FANCC binding, nuclear localization and functional activity of the complex. The human FANCA gene maps to chromosome 16q24.3 and encodes a 1,455 amino acid protein.
- 基因ID
- 2175
- 途径
- DNA Damage Repair
-
