SKAP2 抗体 (AA 1-100)
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- 抗原 See all SKAP2 抗体
- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
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抗原表位
- AA 1-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SKAP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Sheep,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SCAP2
- 亚型
- IgG
- Top Product
- Discover our top product SKAP2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
- 别名
- SCAP2 (SKAP2 产品)
- 别名
- scap2 antibody, 2610021A10Rik antibody, AA960083 antibody, BB137539 antibody, RA70 antibody, SKAP-HOM antibody, Saps antibody, Scap2 antibody, mSKAP55R antibody, PRAP antibody, SAPS antibody, SCAP2 antibody, SKAP55R antibody, Scap55r antibody, SKAP55 antibody, si:dz227h09.6 antibody, si:dz31b14.4 antibody, zgc:158223 antibody, zgc:65975 antibody, src kinase associated phosphoprotein 2 L homeolog antibody, SRC kinase associated phosphoprotein 2 antibody, src family associated phosphoprotein 2 antibody, src kinase associated phosphoprotein 2 antibody, skap2.L antibody, CCC13826_0176 antibody, Skap2 antibody, SKAP2 antibody, skap2 antibody
- 背景
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Synonyms: Fyn associated phosphoprotein SKAP55 homologue, MGC10411, MGC33, PRAP, Pyk2/RAFTK associated protein, Pyk2/RAFTK-associated protein, RA70, Retinoic acid-induced protein 70, SAPS, SKAP-55HOM, SKAP-HOM, skap2, SKAP2_HUMAN, SKAP55 homolog, SKAP55R, Src associated adaptor protein, Src family associated phosphoprotein 2, Src family-associated phosphoprotein 2, src kinase associated phosphoprotein of 55 related protein, Src kinase-associated phosphoprotein 2, Src kinase-associated phosphoprotein 55-related protein, Src-associated adapter protein with PH and SH3 domains.
Background: Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.
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