RAPGEF6 抗体 (AA 601-700)
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- 抗原 See all RAPGEF6 抗体
- RAPGEF6 (Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6))
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抗原表位
- AA 601-700
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAPGEF6 antibody is un-conjugated
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 预测反应
- Human,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RAGEF2
- 亚型
- IgG
- Top Product
- Discover our top product RAPGEF6 Primary Antibody
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) (AA 1012-1110) antibody
RAPGEF6 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) (AA 1012-1111) antibodyRAPGEF6 适用: 人 WB, ELISA, IHC (p), IF, IHC 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6) (AA 145-240) antibodyRAPGEF6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RAPGEF6 (Rap Guanine Nucleotide Exchange Factor (GEF) 6 (RAPGEF6))
- 别名
- RAGEF2 (RAPGEF6 产品)
- 别名
- KIA001LB antibody, PDZ-GEF2 antibody, PDZGEF2 antibody, RA-GEF-2 antibody, RAGEF2 antibody, A530068K01 antibody, AI844632 antibody, BB085664 antibody, C030018K18Rik antibody, Pdzgef2 antibody, Ragef2 antibody, mKIAA4052 antibody, wu:fa12b02 antibody, RAPGEF6 antibody, Rap guanine nucleotide exchange factor 6 antibody, Rap guanine nucleotide exchange factor (GEF) 6 antibody, RAPGEF6 antibody, Rapgef6 antibody, rapgef6 antibody
- 背景
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Synonyms: DKFZp667N084, DKFZp686I15116, KIA001LB, PDZ domain containing guanine nucleotide exchange factor GEF 2, PDZ domain containing guanine nucleotide exchange factor 2, PDZ domain containing guanine nucleotide exchange factor I, PDZ domain-containing guanine nucleotide exchange factor 2, PDZ GEF 2, PDZ GEF2, PDZ-GEF2, PDZGEF 2, PDZGEF2, RA GEF 2, RA GEF2, RA-GEF-2, RAGEF 2, Rap guanine nucleotide exchange factor GEF 6, Rap guanine nucleotide exchange factor 2, Rap guanine nucleotide exchange factor 6, RAPGEF6, RPGF6_HUMAN.
Background: RAPGEF6 is a guanine nucleotide exchange factor (GEF) that is expressed in a variety of tissues. Localizing to the cytoplasm and translocated to the plasma membrane upon ligand binding, RAPGEF6 contains an N-terminal Ras-GEF domain, a cyclic nucleotide monophosphate-binding domain, a PDZ (PSD-95/DlgA/ZO-1) domain, a Ras-associating (RA) domain and a Ras exchanger motif. RAPGEF6 is closely related to RAPGEF2 and both proteins exhibit GEF activity specific towards Rap 1 and Rap 2. In addition, RAPGEF6 is capable of binding to M-Ras via its RA domain. Due to alternative splicing events, two additional isoforms exist for RAPGEF6, namely PDZ-GEF2A and PDZ-GEF2B.
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