SARS-CoV NSP3 抗体 (AA 761-860)
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- 抗原 See all SARS-CoV NSP3 products
- SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))
- 抗原表位
- AA 761-860
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SARS-CoV NSP3 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunocytochemistry (ICC)
- 预测反应
- Human,Mouse,Rat,Dog,Cow
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NSP3
- 亚型
- IgG
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anti-SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3) antibody
SARS-CoV NSP3 适用: SARS Coronavirus-2 (SARS-CoV-2) WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SARS-CoV NSP3 (SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))
- 别名
- NSP3 (SARS-CoV NSP3 产品)
- 物质类
- Viral Protein
- 背景
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Synonyms: Cas/HEF1 associated signal transducer, CHAT, FLJ39664, Novel SH2 containing protein 3, Novel SH2-containing protein 3, NSP 3, PRO34088, SH2 domain containing 3C, SH2 domain containing Eph receptor binding protein 1, SH2 domain containing protein 3C, SH2 domain-containing protein 3C, SH2D3_HUMAN, SH2D3C, Shep1.
Background: Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors (1,2). These receptors, designated TNF-R1 and TNF-R2, are expressed on most cell types (1,3). The majority of TNF functions are primarily mediated through TNF-R1 (1,4). FAN (for factor associated with neutral sphingomyelinase (N-SMase) activation) is an intermediate protein that interacts with TNF-R1 to initiate TNF signaling events. FAN binds to TNF-R1 at the cytoplasmic NSD (N-SMase activating domain), which results in the initiation of the N-SMase pathway (5). N-SMase has been shown to be involved in TNF-induced Raf-1 activation (6). FAN contains four carboxy-terminal WD-repeat domains which appear to be involved in protein-protein interaction. The FAN WD-repeats may mediate the interaction between FAN and TNF-R1 (5).
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