GRB14 抗体 (AA 221-320)
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- 抗原 See all GRB14 抗体
- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
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抗原表位
- AA 221-320
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GRB14 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 特异性
- This antibody may also detect the similar protein GRB10 due to an 83 % sequence similarity in the immunogen sequence.
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GRB 14
- 亚型
- IgG
- Top Product
- Discover our top product GRB14 Primary Antibody
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anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 294-397) antibody
GRB14 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 14-48) antibodyGRB14 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB57897 unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (Internal Region) antibodyGRB14 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) antibodyGRB14 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (Internal Region) antibodyGRB14 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 251-300) antibodyGRB14 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
- 别名
- GRB 14 (GRB14 产品)
- 别名
- GRB14 antibody, AI505286 antibody, growth factor receptor bound protein 14 antibody, GRB14 antibody, grb14 antibody, Grb14 antibody
- 背景
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Synonyms: Growth factor receptor-bound protein 14, GRB14 adapter protein, GRB14
Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
- 基因ID
- 2888
- UniProt
- Q14449
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