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GAS2 抗体 (AA 141-240)

GAS2 适用: 人 ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1713805
发货至: 中国
  • 抗原 See all GAS2 抗体
    GAS2 (Growth Arrest-Specific 2 (GAS2))
    抗原表位
    • 14
    • 14
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 141-240
    适用
    • 56
    • 15
    • 10
    宿主
    • 51
    • 5
    克隆类型
    • 54
    • 2
    多克隆
    标记
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GAS2 antibody is un-conjugated
    应用范围
    • 29
    • 25
    • 12
    • 12
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    预测反应
    Human,Mouse,Rat,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GAS2
    亚型
    IgG
    Top Product
    Discover our top product GAS2 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    GAS2 (Growth Arrest-Specific 2 (GAS2))
    别名
    GAS2 (GAS2 产品)
    别名
    GAS2 antibody, gas2 antibody, si:packt119.1 antibody, GAS-2 antibody, Gas-2 antibody, RGD1563167 antibody, growth arrest specific 2 antibody, growth arrest-specific 2b antibody, growth arrest-specific 2 antibody, GAS2 antibody, gas2b antibody, Gas2 antibody
    背景

    Synonyms: GAS 2, GAS-2, Gas2, GAS2_HUMAN, Growth arrest specic 2, Growth arrest specic protein 2, Growth arrest-specic protein 2, MGC32610.

    Background: Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells. Gas2 is believed to also be involved in the membrane ruffling process. During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues. Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles. Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, lung and kidney. There is no evidence, however, of Gas2 expression in spleen.

    基因ID
    2620
    途径
    Caspase Cascade in Apoptosis
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