DOK7 抗体 (AA 21-120)
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- 抗原 See all DOK7 抗体
- DOK7 (Docking Protein 7 (DOK7))
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抗原表位
- AA 21-120
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOK7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DOK7
- 亚型
- IgG
- Top Product
- Discover our top product DOK7 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- DOK7 (Docking Protein 7 (DOK7))
- 别名
- DOK7 (DOK7 产品)
- 别名
- si:dkey-180b4.3 antibody, si:ch211-164d19.2 antibody, C4orf25 antibody, CMS1B antibody, A930013K19Rik antibody, AW049091 antibody, Dok-7 antibody, EF-12 antibody, Oit5 antibody, RGD1566416 antibody, dok-7 antibody, docking protein 7 antibody, DOK7 antibody, dok7 antibody, Dok7 antibody
- 背景
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Synonyms: Docking protein 7, DOK 7, DOK7, DOK7_HUMAN, Downstream of tyrosine kinase 7, Protein Dok-7.
Background: The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness.
- 途径
- Skeletal Muscle Fiber Development
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