GUCA1C 抗体 (AA 141-209)
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- 抗原 See all GUCA1C 抗体
- GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))
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抗原表位
- AA 141-209
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GUCA1C antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GCAP3
- 亚型
- IgG
- Top Product
- Discover our top product GUCA1C Primary Antibody
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anti-Guanylate Cyclase Activator 1C (GUCA1C) (AA 1-209) antibody
GUCA1C 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Cyclase Activator 1C (GUCA1C) (AA 110-209) antibodyGUCA1C 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Guanylate Cyclase Activator 1C (GUCA1C) (AA 171-199), (C-Term) antibodyGUCA1C 适用: 人 WB 宿主: 兔 Polyclonal RB42656 unconjugated
anti-Guanylate Cyclase Activator 1C (GUCA1C) (AA 1-209) antibodyGUCA1C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))
- 别名
- GCAP3 (GUCA1C 产品)
- 别名
- gcap3 antibody, GCAP3 antibody, guanylate cyclase activator 1C antibody, guca1c antibody, GUCA1C antibody
- 背景
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Synonyms: GCAP 3, Guanylate cyclase activating photoreceptor 3, Guanylate cyclase activator 1C, Guanylyl cyclase activating protein 3, Guanylyl cyclase-activating protein 3, GUC1C_HUMAN, GUCA1C.
Background: The intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating proteins (GCAP). GCAPs are calcium-binding proteins belonging to the calmodulin superfamily and are specifically expressed in retina. GCAP3 (Guanylyl cyclase-activating protein 3), also known as GUCA1C (Guanylate cyclase activator 1C), is a 209 amino acid EF-hand calcium binding protein that is activated by the decrease in calcium from the absorption of light by rhodopsin. Activation of GCAP3 leads to stimulation of guanylate cyclase 1 and 2 (GC1 and GC2), which increases cGMP concentration. Calcium sensitive regulation of GC is essential in recovery of the rod receptor dark state following light exposure. There are two isoforms of GCAP3 that are produced as a result of alternative splicing events.
- 基因ID
- 9626
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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