PRAM1 抗体 (AA 551-650) (HRP)
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- 抗原 See all PRAM1 抗体
- PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
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抗原表位
- AA 551-650
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRAM1 antibody is conjugated to HRP
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PRAM1
- 亚型
- IgG
- Top Product
- Discover our top product PRAM1 Primary Antibody
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anti-PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (AA 1-670) antibody
PRAM1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (AA 551-650) antibodyPRAM1 适用: 人 ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (AA 587-618) antibodyPRAM1 适用: 人 WB 宿主: 兔 Polyclonal RB54864 unconjugated
anti-PML-RARA Regulated Adaptor Molecule 1 (PRAM1) (C-Term) antibodyVerified PRAM1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))
- 别名
- PRAM1 (PRAM1 产品)
- 别名
- PRAM1 antibody, AY665714 antibody, PML-RAR antibody, PRAM-1 antibody, RGD1564330 antibody, PML-RARA regulated adaptor molecule 1 antibody, PML-RAR alpha-regulated adaptor molecule 1 antibody, PRAM1 antibody, Pram1 antibody
- 背景
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Synonyms: PML RAR, PML RARA regulated adaptor molecule 1, PML RARA target gene encoding an Adaptor Molecule 1, PML-RARA-regulated adapter molecule 1, PRAM 1, PRAM, PRAM-1, PRAM_HUMAN, PRAM1.
Background: Complete remission of acute promyelocytic leukemia can be achieved by treating patients with retinoic acid, and PML-RAR-a (promyelocytic leukemia-retinoic acid receptor alpha fusion protein) plays a major role in mediating retinoic acid effects in leukemia cells. The retinoic acid-induced gene, PRAM-1 (PML-RAR-a target gene encoding an adaptor molecule 1) encodes an adaptor protein which is expressed and modulated during normal human myelopoiesis. PRAM-1 expression is hindered by expression of PML-RAR-a. The 718 amino acid PRAM-1 protein contains eight N-terminal proline-rich repeats and several proline residues that are clustered as type I or type II SH3 recognition motifs. PRAM-1 demonstrates expression in hematopoietic tissues and lung.
- 途径
- Regulation of Leukocyte Mediated Immunity
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