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HHAT 抗体 (AA 101-200) (HRP)

HHAT 适用: 人 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1711049
发货至: 中国
  • 抗原 See all HHAT 抗体
    HHAT (Hedgehog Acyltransferase (HHAT))
    抗原表位
    • 14
    • 10
    • 7
    • 6
    • 1
    AA 101-200
    适用
    • 32
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 32
    克隆类型
    • 32
    多克隆
    标记
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HHAT antibody is conjugated to HRP
    应用范围
    • 32
    • 13
    • 13
    • 13
    • 12
    • 12
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human HHAT
    亚型
    IgG
    Top Product
    Discover our top product HHAT Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HHAT (Hedgehog Acyltransferase (HHAT))
    别名
    HHAT (HHAT 产品)
    别名
    RGD1311746 antibody, MART2 antibody, SKI1 antibody, Skn antibody, 2810432O22Rik antibody, AI462858 antibody, AP-2CRE antibody, Tg(TFAP2A-cre)1Will antibody, hedgehog acyltransferase antibody, Hhat antibody, HHAT antibody, hhat antibody
    背景

    Synonyms: 2810432O22Rik, AC115917.1, AI462858, FLJ10724, FLJ34867, Hedgehog acyltransferase, Hhat, HHAT_HUMAN, MART 2, MART-2, MART2, Melanoma antigen recognized by T cells 2, Melanoma antigen recognized by T-cells 2, MGC11697, OTTMUSP00000033669, Protein cysteine N palmitoyltransferase HHAT, Protein-cysteine N-palmitoyltransferase HHAT, RGD1311746, SKI1, Skinny hedgehog protein 1, Skinny hedgehog protein, Skn.

    Background: HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8 % of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.

    基因ID
    55733
    途径
    Hedgehog Signaling
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