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BCL6B 抗体 (AA 141-440) (HRP)

BCL6B 适用: 人 ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1710886
发货至: 中国
  • 抗原 See all BCL6B 抗体
    BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))
    抗原表位
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 141-440
    适用
    • 29
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 28
    • 3
    克隆类型
    • 31
    多克隆
    标记
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This BCL6B antibody is conjugated to HRP
    应用范围
    • 13
    • 13
    • 10
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human BCL6B
    亚型
    IgG
    Top Product
    Discover our top product BCL6B Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    BCL6B (B-Cell CLL/lymphoma 6, Member B (BCL6B))
    别名
    BCL6B (BCL6B 产品)
    别名
    BAZF antibody, ZBTB28 antibody, ZNF62 antibody, Bazf antibody, RGD1563179 antibody, B-cell CLL/lymphoma 6B antibody, B cell CLL/lymphoma 6, member B antibody, B-cell CLL/lymphoma 6, member B antibody, BCL6B antibody, Bcl6b antibody, bcl6b antibody
    背景

    Synonyms: B cell CLL/lymphoma 6, member B zinc finger protein, B-cell CLL/lymphoma 6, member B zinc finger protein, BAZF, Bcl6 associated zinc finger protein, Bcl6-associated zinc finger protein, ZBTB28, Zinc finger protein 62, ZNF62.

    Background: Bcl-6, a transcriptional repressor, binds Stat recognition-like DNA elements and influences germinal center development and cell differentiation. Additionally, Bcl-6 negatively regulates NF_B expression, thereby inhibiting NF_B-mediated cellular functions. Bcl-6b (B-cell CLL/lymphoma 6, member B), also known as ZNF62, BAZF or ZBTB28, is a 480 amino acid nuclear protein that contains one BTB (POZ) domain and five C2H2-type zinc fingers. Expressed ubiquitously with highest expression in placenta and heart, Bcl-6b associates with Bcl-6 and functions as a sequence-specific transcriptional repressor that is thought to be necessary for early B-cell development. The gene encoding Bcl-6b maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.

    途径
    BCR Signaling
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