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IQSEC2 抗体 (AA 851-950) (FITC)

IQSEC2 适用: 小鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN1709553
发货至: 中国
  • 抗原 See all IQSEC2 抗体
    IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
    抗原表位
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 851-950
    适用
    • 18
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 19
    • 1
    克隆类型
    • 20
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IQSEC2 antibody is conjugated to FITC
    应用范围
    • 12
    • 12
    • 6
    • 5
    • 5
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human IQSEC2
    亚型
    IgG
    Top Product
    Discover our top product IQSEC2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
    别名
    IQSEC2 (IQSEC2 产品)
    别名
    BRAG1 antibody, MRX1 antibody, Brag1 antibody, mKIAA0522 antibody, RGD1562109 antibody, IQ motif and Sec7 domain 2 antibody, IQSEC2 antibody, Iqsec2 antibody
    背景

    Synonyms: BRAG1, IQ mot and SEC7 domain-containing protein 2, IQEC2_HUMAN, Iqsec2, KIAA0522, mKIAA0522, MRX1, RP11-258C19.1.

    Background: IQSEC2 is a 1,478 amino acid protein that belongs to the BRAG family and contains one IQ domain, one PH domain and a SEC7 domain. Localizing to the cytoplasm, IQSEC2 is expressed in brain, kidney and small intestine, with weaker levels of expression in placenta, pancreas, ovary, prostate and liver. IQSEC2 is a component of the postsynaptic density at excitatory synapses, and interacts with ARF family members as a guanine nucleotide exchange factor. Through the activation of ARF substrates, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization. The gene encoding IQSEC2 maps to the human X chromosome. Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), a condition characterized by decreased intellectual function. IQSEC2 exists as three isoforms due to alternative splicing events.

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