DAPP1 抗体 (pTyr139) (Cy5)
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- 抗原 See all DAPP1 抗体
- DAPP1 (Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1))
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抗原表位
- pTyr139
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DAPP1 antibody is conjugated to Cy5
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human DAPP1 around the phosphorylation site of Tyr139
- 亚型
- IgG
- Top Product
- Discover our top product DAPP1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DAPP1 (Dual Adaptor of Phosphotyrosine and 3-phosphoinositides (DAPP1))
- 别名
- DAPP1 (DAPP1 产品)
- 别名
- BAM32 antibody, DAPP1 antibody, zgc:111998 antibody, bam32 antibody, Bam32 antibody, dual adaptor of phosphotyrosine and 3-phosphoinositides 1 antibody, dual adaptor of phosphotyrosine and 3-phosphoinositides antibody, dual adaptor for phosphotyrosine and 3-phosphoinositides 1 antibody, DAPP1 antibody, Dapp1 antibody, dapp1 antibody
- 背景
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Synonyms: DAPP1 phospho Y139, p-DAPP1 phospho Y139, B cell adapter molecule of 32 kDa, B lymphocyte adapter protein Bam32, B-cell adapter molecule of 32 kDa, BAM32, DAPP1, DAPP1_HUMAN, DKFZp667E0716, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, Dual adaptor of phosphotyrosine and 3 phosphoinositides, hDAPP1.
Background: B cell adapter molecule is also designated dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC g2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.
- 基因ID
- 27071
- 途径
- BCR Signaling
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