CHTOP 抗体 (AA 31-130) (Cy5)
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- 抗原 See all CHTOP 抗体
- CHTOP (Chromatin Target of PRMT1 (CHTOP))
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抗原表位
- AA 31-130
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHTOP antibody is conjugated to Cy5
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human C1orf77
- 亚型
- IgG
- Top Product
- Discover our top product CHTOP Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CHTOP (Chromatin Target of PRMT1 (CHTOP))
- 别名
- C1orf77 (CHTOP 产品)
- 别名
- C1orf77 antibody, FL-SRAG antibody, FOP antibody, RP1-178F15.2 antibody, SRAG antibody, SRAG-3 antibody, SRAG-5 antibody, pp7704 antibody, 2500003M10Rik antibody, C81330 antibody, Fop antibody, Srag antibody, C25H1orf77 antibody, C3H1orf77 antibody, c1orf77 antibody, chtop antibody, fop antibody, srag antibody, fb17a05 antibody, wu:fb17a05 antibody, wu:fi05e09 antibody, zgc:55292 antibody, zgc:153909 antibody, chromatin target of PRMT1 antibody, chromatin target of PRMT1 S homeolog antibody, chromatin target of PRMT1 protein antibody, chromatin target of PRMT1a antibody, chromatin target of PRMT1b antibody, CHTOP antibody, Chtop antibody, chtop.S antibody, LOC100344922 antibody, chtopa antibody, chtopb antibody
- 背景
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Synonyms: Chromatin target of PRMT1 protein, Chromosome 1 open reading frame 77, CHTOP, CHTOP_HUMAN, DKFZp547E1010, FOP, Friend of PRMT1 protein, MGC131924, MGC86949, OTTHUMP00000035122, OTTHUMP00000035123, Pp7704, RP1 178F15.2, Small arginine- and glycine-rich protein, Small protein rich in arginine and glycine, SRAG.
Background: C1orf77, also known as Friend of PRMT1 protein, is a 248 amino acid protein that plays an essential role in the ligand-dependent activation of estrogen receptor target genes. C1orf77 is tightly associated with chromatin and is modified by both asymmetric and symmetric arginine methylation. Depletion of C1orf77 results in almost complete block of estradiol-induced promter occupancy by the estrogen receptor. Also, complete knockdown of C1orf77 mRNA in adult erythroid progenitors stongly induces fetal hemoglobin, suggesting that C1orf77 is a critical modulator of _-globin gene expression. There are two isoforms of C1orf77 that are produced as a result of alternative splicing events. The gene encoding C1orf77 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
- 基因ID
- 26097
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