MYCBPAP 抗体 (AA 401-500) (Cy5)
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- 抗原 See all MYCBPAP 抗体
- MYCBPAP (MYCBP Associated Protein (MYCBPAP))
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抗原表位
- AA 401-500
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适用
- 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MYCBPAP antibody is conjugated to Cy5
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MYCBPAP
- 亚型
- IgG
- Top Product
- Discover our top product MYCBPAP Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MYCBPAP (MYCBP Associated Protein (MYCBPAP))
- 别名
- MYCBPAP (MYCBPAP 产品)
- 别名
- AMAP-1 antibody, AMAP1 antibody, 4932408B01Rik antibody, AW125474 antibody, COD106 antibody, MYCBP associated protein antibody, Mycbp associated protein antibody, MYCBPAP antibody, Mycbpap antibody
- 背景
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Synonyms: AMAM-1, AMAP-1, AMAP1, AMY-1-binding protein 1, DKFZp434N1415, MYBPP_HUMAN, MYCBP-associated protein, Mycbpap.
Background: AMAP-1 (AMY-1-binding protein 1), also known as AMAM-1 or MYCBPAP (MYCBP associated protein), is a 947 amino acid protein that is expressed specifically in testis and is involved in spermatogenesis and synaptic processes. AMAP-1 colocalizes with MYCBP (AMY-1) in cytoplasm and also localizes to membrane. The gene encoding AMAP-1 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
- 途径
- Sensory Perception of Sound
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