Hepcidin 25 抗体 (AA 60-84) (Biotin)
-
- 抗原 See all Hepcidin 25 (HEPC25) 抗体
- Hepcidin 25 (HEPC25)
-
抗原表位
- AA 60-84
-
适用
- 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Hepcidin 25 antibody is conjugated to Biotin
-
应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from rat Hepcidin
- 亚型
- IgG
- Top Product
- Discover our top product HEPC25 Primary Antibody
-
-
- 应用备注
- IHC-P 1:200-400
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- Hepcidin 25 (HEPC25)
- 别名
- Hepcidin 25 (HEPC25 产品)
- 别名
- HEPC antibody, HFE2B antibody, LEAP1 antibody, PLTR antibody, hepcidin antimicrobial peptide antibody, HAMP antibody
- 背景
-
Synonyms: Hamp, HEPC, HEPC_RAT, HEPC_MOUSE, Hepc20, Hepc25, HEPCIDIN, Hepcidin, Hepcidin 20, Hepcidin 25, Hepcidin antimicrobial peptide, Hepcidin-20, Hepcidin25, HFE2, HFE2B, LEAP 1, LEAP-1, LEAP1, Liver expressed antimicrobial peptide, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor.
Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
- 基因ID
- 84604
- UniProt
- Q99MH3
-
